Octopi

A single drop of blood, from a finger prick, it’s not  Theranos but Octopi, a cool  medical innovation for the 3 billions at risk of malaria: “a low-cost ($250-$500) automated imaging platform that can quantify malaria parasitemia by scanning 1.5 million red blood cells per minute.”

Malaria diagnosis today takes 30 minutes to 1 hour technician’s work on a manual microscope, putting a limit to the capacity of diagnosis centers in poor countries. Octopi combines microscopy, spectroscopy and flow cytometry to deliver a result in few minutes . Screenshot 2019-11-22 at 10.31.18.pngScreenshot 2019-11-22 at 10.32.13.png

Octopi works off a phone charger. It analyzes slides at speeds that are 120 times faster than traditional microscopy. Weighing fewer than seven pounds, it’s portable. And at a do-it-yourself cost of $250 to $500. Its modular architecture means that it takes only changing the camera/imager to detect other parasites. It’s open technology, hardware and software

“We further implement a machine learning classifier and obtain anticipated performance of higher than 90% specificity and sensitivity for parasitemia of 50 parasites per µl and 100% sensitivity and specificity for parasitemia of 150 parasites per µl. Our results suggest that low-cost automated multimodal microscopy combined with machine learning tools have the potential to address the unmet needs for diagnosis of malaria and many other diseases.”

https://www.theatlantic.com/science/archive/2019/08/cheap-automatic-microscope-could-change-how-diseases-are-detected/596440/

https://www.biorxiv.org/content/10.1101/684423v1.full

 

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