I asked it to google and here some links I found

generally the answer seems no, in 2100 sea level will rise and the mose dam won’t save Venice

“The imminent death of Venice due to sea-level rise is barely mentioned in Italy, and yet as long ago as 2010, its most respected marine scientists (ISMAR-CNR) spelled it out: the mobile barriers between the Adriatic and the lagoon known as Mose will be able to stop the flooding for a few decades, but “the sea will eventually rise to a level where even continuous closures will not be able to protect the city from flooding. The question is not if this will happen, only when it will happen”. https://www.theartnewspaper.com/2021/07/21/the-ipccs-predictions-of-sea-level-rise-are-why-italy-should-beg-unesco-to-put-venice-on-its-at-risk-list

‘You’re Responding to Yesterday’s Disasters’: The $6 Billion Floodgates of Venice May Not Be Enough “The sea level is rising higher in the Adriatic’s cul de sac than in other parts of the world; the city is dropping slowly but steadily into the wave (by ten inches during the 20th century) because it’s compacting the ancient sediment it sits on and also because nearby industries pumped out groundwater for decades; and immense cruise ships entering the lagoon act like a high-speed version of climate change, pummeling buildings’ foundations with their wakes”

“its homes aren’t hooked up toa modern sewage system, for instance. Whatever comes out goes into the canals, untreated, and festers in the lagoon’s shallows until the tides wash it away into the Adriatic, twice a day. Activating MOSE blocks that flushing action. In effect, it’s the regional-scale equivalent of a backed-up toilet. The result is tolerable if it gets pressed into service now and then, less so if the gates to the lagoon are shut on a regular basis.”