capex and opex for Rna vaccine depending on dosage of Rna

It comes from this paper https://www.mdpi.com/2076-393X/9/1/3/htm

it strikes me that: a 30 L bioreactor could produce a billion doses a year ?

the bottlenecks are not ion the reaction, harder is getting the comonents tyo the reactor. Than the rna gets wraped in fat and filled in vials, For one bioreactor one needs a lot of fill-in line in parallel